After a war against an enemy from another world breaks out in the South Pacific, a group of freshly recruited U.S. Marines are sent to the front lines.

In the Fabulous Thirties, Doc Savage and his five Amazing Adventurers are sucked into the mystery of Doc's father disappearing in the wilds of South America. The maniacal Captain Seas tries to thwart them at every turn as they travel to the country of Hidalgo to investigate Doc's father's death and uncover a vast horde of Incan gold.

A Hong Kong fashion designer (Jean Claude Van Damme, if you can believe that billing) who had previously been involved in knock offs of major label merchandise, such as "Pumma" running shoes, attempts to go straight with the help of his new partner (Rob Schneider), who is secretly an undercover CIA agent involved in an investigation of the black market. Their main product, jeans, is involved in the knock offs, which brings a representative (Lela Rochon) of the American company to investigate. Paul Sorvino also appears as the head of the CIA operation in Hong Kong. However, just as Schneider is not as he initially seems, everyone in the film switches roles by film's end.